Traveling dentist O'Connell traverses South America on his motorcycle for the 'Eversmile' foundation of New Jersey, in a fight not only against cavities, but also against fear, ignorance, indifference - and established antediluvian dentists. During a stop at a lonesome garage he meets Estella, who is supposed to marry a few days later. However she'd rather come with him - to meet a former boyfriend in another town, she says. Expecting problems, he refuses to take her, but she tricks him into it ...